The Department of Justice (DOJ) has made numerous recent public statements reflecting increased priorities for enforcement, especially in the health care industry. The DOJ has a variety of tools at its disposal to enforce civil and criminal laws and has several methods of obtaining information during health care fraud and abuse investigations. Precious time will be lost, and important steps will be inadvertently missed, if an organization waits until an investigation is underway to decide how it and its employees should react to a government inquiry for information. This presentation will assist entities and individuals in developing a well-thought-out policy for responding to government investigations.